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i had the same problem with a very old (4yr) Syrian hamster, took to the vets, wasn't very helpful they just gave me some cream, made it turn into a scab which fell off , he may of recovered but he died of old age.

maybe it is mites or some kind of skin infection is there any good rodent vets in your area?

also my first mouse i had years ago had very sore skin all over.. i cant remember were it started, but no vet could give us answers , but Ive recently that diet can have a effect and can cause skin reactions so maybe have a look at there diet?
 
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